NewTesela AI is here — AI agents for library design, protocols & optimization. Try it free

Tesela AI

Your Agentic Co-Scientist
for Biological R&D

Autonomous AI agents that design DNA libraries, generate assembly protocols, optimize biomolecules, and analyze experiments — connected to your existing tools via API, SDK, or MCP.

Meet the Agents

Specialized AI for every stage of the Design-Build-Test-Discover cycle. Each agent executes real scientific algorithms, not just text generation.

From idea to 384-variant library in minutes

Library Designer

Describe what you want in natural language or point it at your existing sequence registry. The Library Designer agent creates combinatorial DNA libraries across Golden Gate, Gibson, MoClo, USER, and more — complete with part cost estimates.

  • Simple or combinatorial library design
  • Multi-strategy support (Golden Gate, Gibson, MoClo, USER, PCR)
  • Automatic part reuse from your existing registry
  • Automatic part identification from public databases

Assembly-ready protocols, not just sequences

Library Construction Optimizer

Automatically generate complete assembly protocols with primer design, plate maps, thermocycler programs, and worklists compatible with your lab automation equipment. No more manual protocol writing.

  • Primer design with Tm calculation and validation
  • Automatic plate map generation and PCR assignment
  • Zone gradient thermocycler optimization
  • Optimization of assembly protocol parameters
  • Optimization of assembly overhangs
  • Codon adaptation for protein expression

10x faster convergence with Synthetic Evolution®

Experiment Optimizer

Powered by our patented Synthetic Evolution® machine learning engine. Analyzes your experimental results, predicts top-performing variants, and recommends the next round of experiments to close DBTL cycles faster than any manual approach.

  • Predictive modeling for yield, titer, or binding affinity
  • Generative models for novel sequence leads
  • Automated DBTL cycle recommendations
  • Custom ML model training on your proprietary data

From raw data to actionable insights in seconds

Data Analyst

Upload results from plate readers, sequencers, or analytical instruments. The Data Analyst agent parses, normalizes, and analyzes your experimental data — then recommends next steps based on your objectives.

  • Multi-format data ingestion (CSV, Excel, instrument-native)
  • Automated statistical analysis and visualization
  • Sequence alignment and validation (Sanger, NGS)

From library to plate-ready protocols in one click

Workflow Designer

Coming Soon

Orchestrates end-to-end experimental workflows by automatically composing protocol steps from Library Designer and Library Construction Optimizer outputs. Generates high-throughput worklists for Tecan, Hamilton, Echo, Biomek, and other liquid handlers — eliminating manual protocol translation.

  • Automatic workflow assembly from design to execution
  • High-throughput worklist generation for automation equipment
  • Multi-plate experiment orchestration and tracking
  • Integration with LIMS and lab automation systems
  • Real-time execution monitoring and error handling

Works Where You Work

Four ways to connect

Native

TeselaGen Platform

Access Tesela AI directly within the TeselaGen Platform — including Community Edition. No integration needed. AI agents work natively with your sequences, designs, and experimental data.

TeselaGen Vector Editor with AI integration
Integrations

Connect With Your ELN/LIMS

Tesela AI connects directly to your existing ELN or LIMS. Scientists use AI agents without leaving their notebook — reading sequences, registry data, and assay results, then writing designs and protocols back automatically.

ELN with embedded Tesela AI
Developers

Python SDK & REST API

For computational biologists who work in code. Full programmatic access to every agent capability.

from tesela import TeselaAI

ai = TeselaAI(api_key="tsa_...")

library = ai.design_library(
    parts=["GFP-v1", "RFP-v2", "BFP-v3"],
    strategy="golden_gate",
    target_size=96,
    optimize_for="expression"
)

protocols = library.generate_protocols(
    automation="hamilton"
)
MCPComing Soon

Model Context Protocol

Connect Tesela AI to Claude, ChatGPT, or any MCP-compatible AI host. Scientists access library design, protocol generation, and optimization through their preferred AI interface — Tesela AI handles the biology.

MCP terminal showing Tesela AI connection and library design

What Makes Tesela AI Different

Not a chatbot

These agents execute real algorithms — primer design, assembly optimization, sequence validation, buildability checks, data ingestion and parsing. Years of engineering, not an LLM wrapper.

Proprietary ML: Synthetic Evolution®

Patented biomolecule optimization engine with 10x faster convergence than random screening. Multiple US patents issued on AI-accelerated biotech.

Platform-agnostic

Works with many ELNs, LIMS, or standalone. Connect via REST API, Python SDK, or MCP. You don’t have to switch tools.

Full DBTL loop

The only AI that spans Design → Build → Test → Discover as an integrated cycle. Each experiment informs the next, automatically.

Ready to accelerate your R&D?

Start free with 100 agent runs per month. No credit card required.